Protective Effects of Fermented Glasswort (Salicornia herbacea L.) on Aged Gut Induced by D-Galactose in Rats

نویسندگان

چکیده

Glasswort (Salicornia herbacea L.) is a halophyte plant known to contain high contents of minerals and phytochemicals. The purpose this study was investigate the effect fermented glasswort on gut health in D-galactose (D-gal)-induced aging rats. Forty rats were randomly divided into five groups: control (CON), D-gal alone (CD), plus fructooligosaccharide as positive (FOS, 400 mg/kg), low dose (LGW, 10 high-dose (HGW, 20 mg/kg). Each treatment orally administered each group for eight weeks. All groups except CON (treated with saline) intraperitoneally injected (150 Our results showed that butyric acid among short-chain fatty acids (SCFAs), goblet cells colon, thickness mucus layer colon increased groups. In addition, reduced levels thiobarbituric acid-reactive substances (TBARS, related oxidative stress marker) expression inflammation-related proteins such IL-1β. These suggest can improve age-related health.

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ژورنال

عنوان ژورنال: Applied sciences

سال: 2023

ISSN: ['2076-3417']

DOI: https://doi.org/10.3390/app13148386